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Cambridge’s Aura Biosciences pioneers the new science of nanomedicines with nanosmart particles January 25, 2010

Posted by HubTechInsider in Health Care IT, Nanotechnology, Startups, Venture Capital.
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Cambridge’s Aura Biosciences pioneers the new science of nanomedicines with nanosmart particles

Elisabeth de los Pinos is a molecular biologist and founder and President of Aura Biosciences, a startup in Cambridge, Massachusetts. In late 2007, the Barcelona native learned that a cancer research institute in Germany had created a nanoparticle with dimensions that would allow it to pass easily through blood vessels (one nanomater equals a billionth of a meter). And because nanoparticles are multifunctional, she figured they would be the perfect vehicle to carry a homing device, a technology she then located at a British research center.

De los Pinos got exclusive licenses for both technologies and then went to work. She and her team genetically modified the nanoparticle by adding a targeting peptide to it. The result was a structure that can protect, target, and deliver the drug inside it. If the drug can be restricted to the cancer site, oncologists will be able to up the dosage without inflicting the damage elsewhere. higher doses mean higher efficacy.

Anticancer nanomedicines are very hot. The hope is that this technology will provide drugs with the ability to simultanteously treat, target and be monitored in the body.

De los Pinos, who has trademarked her new technology as nanosmart particles, is part of a cadre of nanoentrepreneurs, many of whom have found particles as potential delivery vehicles but are not necessarily using new medicines. Alot is currently known about the good and bad effects of approved drugs. If a drug is effective and widely used and there is a way to make it more effective, it makes sense to promote grater effectiveness in the drug’s employment. The target is well known; It is the aiming of the drugs that is now improving.

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Lexington’s StreamBase Systems pioneers CEP (Complex Event Processing) database technology January 24, 2010

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Lexington’s StreamBase Systems pioneers CEP (Complex Event Processing) database technology

CEP allows users to analyze information as it streams in, a huge step up from relation databases, in which data needs to be stored before being processed. Whereas most databases can handle hunded of bits of data per second, StreamBase’s platform can process hundreds of thousands of pieces of info, or “events”, per second: emails, Facebook posts, signals intelligence, audio and video streams – or a combination.

Pair brute force processing power with realtime analysis, and you get a sense of how CEP can be useful to an intelligence agency. The platform can search for specific combinations of words or numbers, so if an al-Qaeda suspect whose email address is known started getting messages that included, say, “bomb” and “Washington” and “Martyrdom”, an alert would go off.

As terrorist operations are frequently controlled and planned via the Internet, a major commercial application of CEP database technology is the ability to tap into the stream of Internet communications data and make realtime decisions based on that information.

Mark Palmer is the President of StreamBase Systems, headquartered in Lexington, Massachusetts.

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Cambridge’s ATG, Inc., acquires Seattle’s InstantService, Inc., for $17 Million January 24, 2010

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Cambridge’s ATG, Inc., (Art Technology Group) an ecommerce technology company, acquires Seattle’s InstantService, Inc., a provider of live chat services used predominantly in live tech help situations, for $17 Million.

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Chelmsford’s Aspect Software Inc acquires St. Charles, MO’s Quilogy, for undisclosed terms January 24, 2010

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Chelmsford’s Aspect Software Inc., a communications and contact center software developer, acquires St. Charles, MO’s Quilogy, an IT services company, for undisclosed terms.

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Islandia, NY’s CA, Inc., acquires Waltham’s Oblicore for undisclosed terms January 24, 2010

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Islandia, NY’s CA, Inc.,an IT management software company, acquires Waltham’s Oblicore, a provider of Service Level Management (SLM) software for enterprises and service providers, for undisclosed terms.

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Boston’s CitySquares Online, Inc., acquires Boston’s Yokel.com, for undisclosed terms January 24, 2010

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Boston’s CitySquares Online, Inc., a provider of Web-based hyper-local search technologies, acquires Boston’s Yokel.com, a local products searches provider, for undisclosed terms.

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Arlington’s Optics For Hire, Inc., acquires Bedford’s Actuality Systems, for undisclosed terms January 24, 2010

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Arlington’s Optics For Hire, Inc., a creator of hologram-like images from 3-D digital data, acquires Bedford’s Actuality Systems, a maker of visualization systems for medicine, oil and gas exploration, and other applications, for undisclosed terms.

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Bedford’s Progress Software acquires Santa Clara’s Savvion for $49 Million January 22, 2010

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Bedford’s Progress Software, a maker of systems for integrating enterprise software applications acquires Santa Clara’s Savvion, a maker of business process management software, for $49 Million.

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Cambridge’s Virtify raises $15 Million in a Series A Round January 22, 2010

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Cambridge’s Virtify, a provider of Web-based document management software for life sciences firms, raises $15 Million in a Series A Round from a group of undisclosed investors.

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Cambridge’s OneForty Inc. raises $1.85 Million in a Series A Round January 22, 2010

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Cambridge’s OneForty Inc., a Twitter application store and e-commerce platform for developers of applications that integrate with Twitter, raises $1.85 Million in a Series A Round from investors including Flybridge Capital Partners, Javelin Venture Partners, Jefferies & Co, Dave McClure, and Roger Ehrenberg.

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Newton’s Life Image raises $2.2 Million January 22, 2010

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Newton, MA -based Life Image, a provider of software that enables doctors to share radiology images with colleagues around the globe via cloud-based in-boxes, raises $2.2 Million from a group of investors including Long River Ventures, Massachusetts Technology Development Corporation, and Partners Innovation Fund.

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Norwood’s Gryphon Networks Inc. raises $7 Million January 22, 2010

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Norwood’s Gryphon Networks Inc., a developer of communications and regulatory-compliance technologies, raises $7 Million in a Series C round of capital from a group of investors led by Symmetric Capital.

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Lynnfield’s AcadiaSoft raises $4 Million January 22, 2010

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Lynnfield’s AcadiaSoft, a maker of software for managing derivative investments, raises $4 Million from a group of investors led by HSBC Holdings, ICAP, and JP Morgan Chase & Co.

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Andover’s Pixtronix, Inc., display technology developer, raises $19 Million in venture capital January 6, 2010

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Andover’s Pixtronix, Inc., display technology developer, raises $19 Million in venture capital from a group of investors including Atlas Ventures, Kleiner Perkins Caulfield Beyers, Duff Ackerman, Goodrich Ventures, and Gold Hill Capital.

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Billerica’s Jingle Networks raises $6.75 Million in new startup capital January 5, 2010

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Billerica’s Jingle Networks, a website and service that allows callers to obtain free directory assistance for telephone numbers, raises $6.75 Million in a Series E round of new startup capital from a group of investors including First Round Capital, Lead Dog Ventures, Liberty Associated Partners, Rose Tech Ventures, Goldman Sachs, the Hearst Corporation, Flybridge Capital, IDG Ventures, and Comcast Interactive Capital.

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Boston’s Digital Lumens, Inc., a high efficiency lighting company, raises $5 Million in new equity funding January 5, 2010

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Boston’s Digital Lumens, Inc., a high efficiency lighting company, raises $5 Million in new equity funding from a group of investors led by Flybridge Capital Partners, Stata Venture Partners, and Black Coral Capital.

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Waltham’s ViewFinity, a SaaS desktop & server software maker, raises $8.6 Million in a Series B round of financing January 3, 2010

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Waltham, Massachusetts – based ViewFinity, a provider of Software-as-a-Service software for the support and management of desktops, laptops, and Windows servers, raises $8.6 Million in a Series B round of equity capital led by a group of investors including JK&B Capital and Giza Venture Capital.

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Boston’s SCVNGR, location-aware mobile games maker, raises $4 Million January 3, 2010

Posted by HubTechInsider in Mobile Software Applications, Startups, Venture Capital, Wireless Applications.
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Boston’s SCVNGR, a maker of a mobile software platform that lets you build location-based games compatible with any mobile phone, raises $4 Million from a group of investors including Google Ventures and Highland Capital.

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